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In a further embodiment, the present invention is directed toward a modified TetR(Z) protein comprising an amino acid substitution at an amino acid position selected from the group consisting of positions 63, 74, 75, 95, 99, 100, 103, 104, 105, 107, 118, 137, 165, 166, 167, 181, 185, and 189 of the TetR(Z) protein as depicted in SEQ ID NO: 50, wherein said modified TetR(Z) protein binds a TetR(Z) operator sequence with greater affinity in the presence of tetracycline than in the absence of tetracycline, where: the amino acid substitution at position 63 is asparagine, the amino acid substitution at position 74 is valine; the amino acid substitution at position 75 is valine; the amino acid substitution at position 95 is glutamine; the amino acid substitution at position 99 is selected from the group consisting of glycine and glutamic acid; the amino acid substitution at position 99 is glycine; the amino acid substitution at position 99 is glutamic acid; the amino acid substitution at position 100 is arginine; the amino acid substitution at position 100 is glutamic acid; the amino acid substitution at position 103 is glutamic acid; the amino acid substitution at position 104 is alanine; the amino acid substitution at position 105 is histidine; the amino acid substitution at position 107 is serine; the amino acid substitution at position 118 is valine; the amino acid substitution at position 137 is selected from the group consisting of arginine, lysine, and histidine; the amino acid substitution at position 165 is cysteine; the amino acid substitution at position 166 is leucine; the amino acid substitution at position 167 is valine; the amino acid substitution at position 181 is glycine; the amino acid substitution at position 185 is tryptophan; and the amino acid substitution at position 189 is histidine?
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Sarah Glasser has joined the Center for Family Law.
was born and raised in Tulsa, Oklahoma, graduating from Washington University in St. Louis in 2000 with a B.A. in East Asian Studies and The University of Tulsa College of Law in 2003. After law school she moved back to St. Louis and then began practicing law in 2004. Sarah practices exclusively in the area of Missouri family law and domestic relations. Sarah is also a certified Guardian ad Litem, representing the best interests of children in contested custody cases.
She is committed to providing her clients’ sound legal advice that gives them a realistic perspective on the legal system and what they can expect from it, rather than simply telling them what they would like to hear.
The choice of a family lawyer is very important. Sarah wants to develop a partnership with her client so together they can develop solutions to the current issues they are facing as well as aid in their growth and provide for a bright future.
Missouri Bar Association
Woman’s Place – Former Board Member, 2006-2014; Co-Secretary 2012-2014
Woman’s Place – Human Resource and Program Committees, 2014 to present
Washington University in St. Louis (B.A. 2000)
Duke University, Study Abroad in China (1998)
University of Tulsa, College of Law (J.D. 2003)
Sarah M. Teal, Domestic Violence: The Quest for Zero Tolerance in the United States and China: A Comparative Analysis of the Legal and Medical Aspects of Domestic Violence in the United States and China
5 J.L. Soc’y 313 (Fall, 2003)
Glasser, Sarah M. “Ending Family Violence, The Effects of Violence on Children.” The St. Louis Women On The Move. May 2006, Vol. 3 No.2: 20-21. Print.